Capping And Lamination Of Tablets

Ejection issues could lead to lamination.

Capping and lamination of tablets. Capping and lamination are common defects that occur during tablet manufacturing. Compressing the tablet too thin the only common factor between capping and lamination usually occurs at precompression causing the tablets to compress in layers and the layers will separate as tablets cool or the bottom layer will separate from top during ejection. Lamination is also caused by the presence of a large amount of fines in the granulations. As the air is released when the upper punch die tip is raised capping only occurs at the top of the tablet.

Lamination is separation that occurs at any other part of the tablet except the top or bottom. This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate. Although the method is widely used there are still significant challenges with achieving a high quality compact. First lamination is caused by air being trapped in the tablet especially among the granules or particles.

Capping happens when the upper or lower part of a tablet separates horizontally photo as the press ejects the tablet.