Capping And Lamination

Moreover lamination is caused by either there being an.
Capping and lamination. Capping happens when the upper or lower part of a tablet separates horizontally photo as the press ejects the tablet. Although the method is widely used there are still significant challenges with achieving a high quality compact. Previous publications showed that changing the unloading conditions triaxial decompression loaded ejection made it possible to mitigate capping. Furthermore a stereomicroscope stereo discovery v8.
In the present study a systematic study of the effect of the unloading. Lamination is the term used for a split in the tablet anywhere but at the top. Carl zeiss oberkochen germany was only used to illustrate the difference between capping and lamination. Capping and lamination are classical industrial issues that can be challenging during the scale up of solid dosage forms.
A cross section of a tablet without capping or. Capping and lamination are common defects that occur during tablet manufacturing. Main reason for lamination is attributed to presence of bands cracks in tablet whereas presence of air in. Lamination is separation that occurs at any other part of the tablet except the top or bottom.
It is nevertheless important to diagnose the lamination issue correctly to ensure that proper steps are taken to solve the problem. Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process. In this context there is an urgent need for approaches to overcome the occurrences of capping and lamination. Usually capping and lamination occur during or after tablet manufacturing and may therefore influence follow up processes such as the coating.
Removing some or all the fines through the 100 mesh screen will reduce the chances of lamination occurring by a higher percentage. The capping or lamination indices were determined in triplicate whereby the total number of investigated tablets n t was 20 for each measurement. Lamination is essentially the same as capping and with similar causes.